As Stuart said 300ppi is a good base for most print because the RIP can throw out the extra data of the larger image that it doesn’t need when processing the image for a lower lpi and the files are not that much larger than the 266ppi files are. The two most typical lpi’s that we use for products at work are 133lpi and 150lpi, so the image should be at 266ppi or 300 ppi. Technically speaking ppi for print should be at twice the lpi that you are going to print at. Sure, there are other reasons that InDesign files can get huge, but images are the main problem I’ve encountered. InDesign places the image at the proper size, makes a much smaller proxy image, and the next time you do a Save As, your file size should drop considerably. Now save the file and reimport it into InDesign. The solution: Open your file in Photoshop, choose Image > Image Size, turn off the Resample Image checkbox (if you don’t want the image data to change), then set the resolution to something reasonable (such as 225 or 250 ppi). But when you import a 72 ppi image, InDesign saves the entire image as the preview! It essentially embeds the whole thing because it’s trying to save a low res (72 ppi) version of your 72 ppi image. Now here’s the rub: When you import an image, InDesign saves a low-res “thumbnail” preview of it, right? That’s what’s stored in the InDesign file itself (so you can still see the image if the original on-disc image is missing). So you import it into InDesign and scale it down to the proper size, which increases its effective resolution (watch the Info palette to see original vs. It may be a 17 MB, 3000 x 2000 digital capture, but if it’s saved at 72 ppi, then it’s about 41 by 27 inches large. Unfortunately, many cameras save their files at 72 ppi (pixels per inch, sometimes called dpi). These images were probably saved from a digital camera to disk, and then imported directly into InDesign. However, in this case, the problem is, in fact, your images. That clears out any gunk that has accumulated while you’ve been working on the file. The first thing to always try when trying to reduce file size is to choose File > Save As. There are a number of things that can make your InDesign files huge. Ironically, I know the answer to this one because of my long history with QuarkXPress, which also exhibits this curious phenomenon. jpg images, why would this file be so large? If it’s not saving any image data and merely linking 500. The linked photos themselves are high resolution, around 2-3MB a piece. Doing a quick preflight check shows that there are no embedded images nor saved image previews. I have a 60+ page CS3 file that saves at around 450MB and growing.